Additional file 1 of Transplanted allogeneic cardiac progenitor cells secrete GDF-15 and stimulate an active immune remodeling process in the ischemic myocardium

Mishra, Rachana; Saha, Progyaparamita; Datla, Srinivasa Raju; Mellacheruvu, Pranav; Gunasekaran, Muthukumar; Guru, Sameer Ahmad; Fu, Xubin; Chen, Ling; Bolli, Roberto; Sharma, Sudhish; Kaushal, Sunjay

doi:10.6084/m9.figshare.20353580.v1

12967_2022_3534_MOESM1_ESM.pptx (17.44 MB)

Additional file 1 of Transplanted allogeneic cardiac progenitor cells secrete GDF-15 and stimulate an active immune remodeling process in the ischemic myocardium

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posted on 2022-07-22, 03:16 authored by Rachana Mishra, Progyaparamita Saha, Srinivasa Raju Datla, Pranav Mellacheruvu, Muthukumar Gunasekaran, Sameer Ahmad Guru, Xubin Fu, Ling Chen, Roberto Bolli, Sudhish Sharma, Sunjay Kaushal

Additional file 1: Figure S1. Invitro co-culture assay with rCPCs/rCPCsGDF15KD with BN rat spleenocytes for 5 day and Flow cytometry plot gated on human CD4 T cells. CD48 measured by FACS. Figure S2. Whole hearts were also obtained on day 5 for immunohistochemistry studies. Images of GDF15, and DAPI staining.

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American Heart Association National institute of health Maryland Stem Cell Research Fund

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Cardiac progenitor cells Myocardial ischemia Growth differentiation factor 15 Immunomodulatory properties T-regulatory cells Macrophages

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Additional file 1 of Transplanted allogeneic cardiac progenitor cells secrete GDF-15 and stimulate an active immune remodeling process in the ischemic myocardium

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American Heart Association National institute of health Maryland Stem Cell Research Fund

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