12890_2019_906_MOESM1_ESM.docx (49.69 kB)
Additional file 1: of Severe exacerbations in moderate-to-severe asthmatics are associated with increased pro-inflammatory and type 1 mediators in sputum and serum
journal contribution
posted on 2019-08-09, 04:06 authored by Michael Ghebre, Pee Pang, Dhananjay Desai, Beverley Hargadon, Chris Newby, Joanne Woods, Laura Rapley, Suzanne Cohen, Athula Herath, Erol Gaillard, Richard May, Chris BrightlingTable S1. Sputum and serum mediators lower limit of detection (LLD) and lower limit of quantification (LLQ). Table S2. Clinical characteristics at children assessed either at stable visits or following admission to hospital for an acute-severe exacerbation of asthma. Table S3. Geometric mean (95% CI) sputum mediator concentrations (pg/ml) for all first stable and first exacerbation visits. Table S4. Geometric mean (95% CI) serum mediator concentrations (pg/ml) for all first stable and first exacerbation visits. Table S5. ROC area under the curve (AUC) (95% CI) for sputum and serum mediators between first stable and first exacerbation visits. (DOCX 49 kb)