12929_2019_557_MOESM1_ESM.docx (166.96 kB)

Additional file 1: of Penfluridol triggers cytoprotective autophagy and cellular apoptosis through ROS induction and activation of the PP2A-modulated MAPK pathway in acute myeloid leukemia with different FLT3 statuses

Download (166.96 kB)
journal contribution
posted on 31.08.2019, 08:24 by Szu-Yuan Wu, Yu-Ching Wen, Chia-Chi Ku, Yi-Chieh Yang, Jyh-Ming Chow, Shun-Fa Yang, Wei-Jiunn Lee, Ming-Hsien Chien
Figure S1. Inhibition of reactive oxygen species (ROS) reverses penfluridol-induced LC3 turnover and p62 degradation in HL-60 acute myeloid leukemia cells. Figure S2. Inhibition of p38 mitogen-activated protein kinase (MAPK) reverses penfluridol-induced extracellular signal-regulated kinase (ERK) dephosphorylation in U937 and HL-60 acute myeloid leukemia cells. (DOCX 166 kb)

Funding

Wan Fang Hospital

History

Exports