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MOESM1 of Intrinsic and extrinsic epigenetic age acceleration are associated with hypertensive target organ damage in older African Americans

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posted on 2019-10-23, 08:28 authored by Jennifer Smith, Jeremy Raisky, Scott Ratliff, Jiaxuan Liu, Sharon Kardia, Stephen Turner, Thomas Mosley, Wei Zhao
Additional file 1: Table S1. Regression results for the association between epigenetic age acceleration and blood pressure in GENOA African Americans (n = 1390). Table S2. Beta coefficient for IEAA association with target organ damage measures in Model 2 and with Model 3 covariates added separately. Table S3. Regression results for the association between epigenetic age acceleration and target organ damage measures among GENOA African Americans, adjusting for array type or limiting analyses to those with EPIC data. Table S4. Regression results for the association between epigenetic age acceleration and target organ damage measures among GENOA African Americans, adjusting for educational attainment. Table S5. Regression results for the association between epigenetic age acceleration and target organ damage measures among GENOA African Americans with hypertension. Table S6. Heritability estimates of epigenetic age acceleration and target organ damage measures among GENOA African Americans. Figure S1. Scatterplots of DNAm age and epigenetic age acceleration from 102 duplicated samples using 450 K and EPIC array data. Figure S2. Distributions of epigenetic age acceleration measures.

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National Heart, Lung, and Blood Institute

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