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MOESM1 of Determining post-treatment surveillance criteria for predicting the elimination of Schistosoma mansoni transmission

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posted on 2019-09-16, 03:11 authored by Jaspreet Toor, James Truscott, Marleen Werkman, Hugo Turner, Anna Phillips, Charles King, Graham Medley, Roy Anderson
Additional file 1: Figure S1. Simulations achieving elimination or resurgence after stopping mass drug administration (50 simulations are shown for each scenario). a Low adult burden setting; treating 85% SAC + 40% adults annually for 12 years. b Low adult burden setting; treating 100% SAC + 100% adults annually for 8 years. c High adult burden setting; treating 100% SAC + 100% adults annually for 10 years. Table S1. Positive and negative predictive values (PPV and NPV) whilst sampling 200 individuals across the entire community (population size is 500) using single Kato-Katz on two samples per individual. Values are shown for high adult burden setting where treatment has been carried out for 100% school-aged children and 100% adults annually for 10 years. For each prevalence threshold, values highlighted in blue are time points for which PPV ≥ 0.9 and in grey are time points for which PPV < 0.9. PPV shown in Fig. 1.

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Bill & Melinda Gates Foundation

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