Additional file 1: of Distinct promoter methylation profile reveals spatial epigenetic heterogeneity in 2 myeloma patients with multifocal extramedullary relapses

Materials and methods. Table S1. Primer sequences. Table S2. Clonality detected in the two patients with multiple extramedullary diseases. Figure S1, Assay of sensitivity of SHP1 and CDH1 by methylated methylation-specific polymerase chain reaction of the methylated positive control. Figure S2. Sequencing of methylated methylation-specific polymerase chain reaction (M-MSP) products. Figure S3. Methylation-specific polymerase chain reaction (MSP) study of SHP1 in normal peripheral blood. (DOCX 3973 kb)