Additional file 1: of A prognostic CpG score derived from epigenome-wide profiling of tumor tissue was independently associated with colorectal cancer survival

Table S1. Characteristics of patients in the study cohort and the validation cohort. Table S2. Genes used to define CIMP status in previous studies that were available on the 450k methylation array. Table S3. CpG sites identified in the study cohort that were included or excluded in the final analyses. Table S4. Association of the coefficient score with characteristics of colorectal cancer patients in the study cohort and the validation cohort. Figure S1. Heatmaps showing the methylation level of the seven CpG sites across all the patients in the study cohort (A) and the validation cohort (B), respectively. Figure S2. Unadjusted Kaplan–Meier curves of the association of the coefficient score with disease-specific survival and non-disease-specific survival in the validation cohort. (DOCX 2549 kb)