Reference list | upload_1 Mapped IDs: 14997 out of 15062 | 752 out of 772 Unmapped IDs: 6702 | 266 Multiple mapping information: 944 | 32 Analysis Type: PANTHER Overrepresentation Test (Released 20181010) Annotation Version and Release Date: GO Ontology database Released 2018-09-06 Analyzed List: upload_1 (Homo sapiens) Reference List: measured_genes.txt (Homo sapiens) There are duplicate IDs in the file. The unique set of IDs will be used. Test Type: FISHER Correction: BONFERRONI Bonferroni count: 7833 GO biological process complete measured_genes.txt - REFLIST (15062) upload_1 (772) upload_1 (expected) upload_1 (over/under) upload_1 (fold Enrichment) upload_1 (P-value) T cell activation involved in immune response (GO:0002286) 39 12 2.00 + 6.00 3.56E-02 acute inflammatory response (GO:0002526) 51 14 2.61 + 5.36 1.79E-02 antimicrobial humoral response (GO:0019730) 58 15 2.97 + 5.05 1.48E-02 defense response to bacterium (GO:0042742) 138 33 7.07 + 4.67 6.92E-08 regulation of acute inflammatory response (GO:0002673) 72 17 3.69 + 4.61 9.11E-03 response to fatty acid (GO:0070542) 75 17 3.84 + 4.42 1.48E-02 neutrophil degranulation (GO:0043312) 439 95 22.50 + 4.22 3.91E-25 neutrophil activation involved in immune response (GO:0002283) 443 95 22.71 + 4.18 7.14E-25 neutrophil mediated immunity (GO:0002446) 448 96 22.96 + 4.18 3.75E-25 neutrophil activation (GO:0042119) 448 96 22.96 + 4.18 3.75E-25 granulocyte activation (GO:0036230) 453 96 23.22 + 4.13 7.87E-25 humoral immune response (GO:0006959) 130 27 6.66 + 4.05 7.55E-05 leukocyte degranulation (GO:0043299) 459 95 23.53 + 4.04 7.42E-24 myeloid leukocyte mediated immunity (GO:0002444) 468 96 23.99 + 4.00 6.88E-24 myeloid cell activation involved in immune response (GO:0002275) 471 95 24.14 + 3.94 4.03E-23 cytokine production (GO:0001816) 126 25 6.46 + 3.87 5.77E-04 leukocyte activation involved in immune response (GO:0002366) 541 107 27.73 + 3.86 6.64E-26 cell activation involved in immune response (GO:0002263) 544 107 27.88 + 3.84 9.97E-26 positive regulation of cytokine secretion (GO:0050715) 98 19 5.02 + 3.78 2.83E-02 myeloid leukocyte activation (GO:0002274) 510 98 26.14 + 3.75 1.48E-22 leukocyte mediated immunity (GO:0002443) 560 107 28.70 + 3.73 8.35E-25 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains (GO:0002460) 116 22 5.95 + 3.70 6.78E-03 positive regulation of leukocyte mediated immunity (GO:0002705) 102 19 5.23 + 3.63 4.70E-02 inflammatory response (GO:0006954) 349 65 17.89 + 3.63 2.79E-13 regulation of adaptive immune response (GO:0002819) 134 23 6.87 + 3.35 1.75E-02 leukocyte activation (GO:0045321) 765 130 39.21 + 3.32 1.31E-26 regulated exocytosis (GO:0045055) 615 104 31.52 + 3.30 2.70E-20 regulation of inflammatory response (GO:0050727) 276 46 14.15 + 3.25 3.84E-07 regulation of leukocyte mediated immunity (GO:0002703) 156 26 8.00 + 3.25 6.34E-03 defense response to other organism (GO:0098542) 291 48 14.92 + 3.22 1.99E-07 adaptive immune response (GO:0002250) 225 37 11.53 + 3.21 4.23E-05 cell activation (GO:0001775) 878 143 45.00 + 3.18 5.06E-28 response to bacterium (GO:0009617) 413 67 21.17 + 3.17 3.85E-11 regulation of cytokine secretion (GO:0050707) 142 23 7.28 + 3.16 4.13E-02 immune effector process (GO:0002252) 809 129 41.47 + 3.11 5.16E-24 regulation of reactive oxygen species metabolic process (GO:2000377) 151 24 7.74 + 3.10 3.46E-02 exocytosis (GO:0006887) 690 105 35.37 + 2.97 2.09E-17 negative regulation of cytokine production (GO:0001818) 211 32 10.81 + 2.96 2.35E-03 response to lipopolysaccharide (GO:0032496) 242 36 12.40 + 2.90 6.61E-04 response to molecule of bacterial origin (GO:0002237) 256 37 13.12 + 2.82 8.42E-04 regulation of immune effector process (GO:0002697) 312 45 15.99 + 2.81 3.72E-05 immune response (GO:0006955) 1209 173 61.97 + 2.79 8.78E-29 defense response (GO:0006952) 886 125 45.41 + 2.75 8.47E-19 positive regulation of cytokine production (GO:0001819) 334 47 17.12 + 2.75 3.39E-05 regulation of cytokine production (GO:0001817) 533 75 27.32 + 2.75 9.11E-10 regulation of T cell activation (GO:0050863) 256 36 13.12 + 2.74 2.28E-03 positive regulation of defense response (GO:0031349) 300 42 15.38 + 2.73 2.61E-04 leukocyte differentiation (GO:0002521) 258 36 13.22 + 2.72 2.69E-03 response to other organism (GO:0051707) 633 88 32.44 + 2.71 7.67E-12 response to external biotic stimulus (GO:0043207) 633 88 32.44 + 2.71 7.67E-12 secretion by cell (GO:0032940) 825 114 42.29 + 2.70 3.17E-16 regulation of leukocyte activation (GO:0002694) 411 56 21.07 + 2.66 3.56E-06 immune response-regulating signaling pathway (GO:0002764) 331 45 16.97 + 2.65 2.27E-04 positive regulation of leukocyte activation (GO:0002696) 265 36 13.58 + 2.65 6.76E-03 response to biotic stimulus (GO:0009607) 661 89 33.88 + 2.63 3.27E-11 immune response-regulating cell surface receptor signaling pathway (GO:0002768) 255 34 13.07 + 2.60 1.79E-02 regulation of lymphocyte activation (GO:0051249) 346 46 17.73 + 2.59 2.55E-04 regulation of defense response (GO:0031347) 557 74 28.55 + 2.59 1.51E-08 regulation of immune response (GO:0050776) 740 98 37.93 + 2.58 2.39E-12 regulation of cell activation (GO:0050865) 438 58 22.45 + 2.58 6.47E-06 secretion (GO:0046903) 908 120 46.54 + 2.58 8.03E-16 positive regulation of cell activation (GO:0050867) 274 36 14.04 + 2.56 1.10E-02 regulation of cell-cell adhesion (GO:0022407) 315 41 16.15 + 2.54 2.35E-03 lymphocyte activation (GO:0046649) 292 38 14.97 + 2.54 6.55E-03 activation of immune response (GO:0002253) 346 45 17.73 + 2.54 6.15E-04 positive regulation of secretion (GO:0051047) 309 40 15.84 + 2.53 3.70E-03 regulation of innate immune response (GO:0045088) 302 39 15.48 + 2.52 5.45E-03 immune response-activating signal transduction (GO:0002757) 297 38 15.22 + 2.50 9.20E-03 positive regulation of immune response (GO:0050778) 517 66 26.50 + 2.49 1.50E-06 positive regulation of immune system process (GO:0002684) 741 94 37.98 + 2.47 1.39E-10 regulation of hemopoiesis (GO:1903706) 333 42 17.07 + 2.46 4.35E-03 negative regulation of immune system process (GO:0002683) 336 42 17.22 + 2.44 5.04E-03 innate immune response (GO:0045087) 473 59 24.24 + 2.43 2.79E-05 regulation of immune system process (GO:0002682) 1134 136 58.12 + 2.34 5.97E-15 immune system process (GO:0002376) 1921 221 98.46 + 2.24 9.25E-26 chemotaxis (GO:0006935) 384 44 19.68 + 2.24 2.54E-02 taxis (GO:0042330) 386 44 19.78 + 2.22 2.73E-02 response to wounding (GO:0009611) 436 49 22.35 + 2.19 1.17E-02 cytokine-mediated signaling pathway (GO:0019221) 479 52 24.55 + 2.12 1.27E-02 positive regulation of transport (GO:0051050) 763 82 39.11 + 2.10 1.44E-05 regulation of response to external stimulus (GO:0032101) 598 62 30.65 + 2.02 5.32E-03 response to external stimulus (GO:0009605) 1493 153 76.52 + 2.00 1.06E-11 regulation of cell adhesion (GO:0030155) 537 55 27.52 + 2.00 2.99E-02 response to lipid (GO:0033993) 667 68 34.19 + 1.99 3.04E-03 cell migration (GO:0016477) 639 65 32.75 + 1.98 4.85E-03 locomotion (GO:0040011) 911 92 46.69 + 1.97 2.58E-05 localization of cell (GO:0051674) 726 73 37.21 + 1.96 1.48E-03 cell motility (GO:0048870) 726 73 37.21 + 1.96 1.48E-03 cellular response to cytokine stimulus (GO:0071345) 750 75 38.44 + 1.95 1.40E-03 response to cytokine (GO:0034097) 819 80 41.98 + 1.91 1.20E-03 vesicle-mediated transport (GO:0016192) 1535 147 78.68 + 1.87 6.66E-09 positive regulation of multicellular organismal process (GO:0051240) 1327 127 68.02 + 1.87 3.48E-07 cellular response to oxygen-containing compound (GO:1901701) 786 72 40.29 + 1.79 4.70E-02 cell surface receptor signaling pathway (GO:0007166) 1783 163 91.39 + 1.78 9.88E-09 regulation of response to stress (GO:0080134) 1117 100 57.25 + 1.75 1.31E-03 positive regulation of response to stimulus (GO:0048584) 1758 154 90.11 + 1.71 1.21E-06 response to oxygen-containing compound (GO:1901700) 1186 101 60.79 + 1.66 1.09E-02 regulation of multicellular organismal process (GO:0051239) 2351 199 120.50 + 1.65 1.52E-08 regulation of transport (GO:0051049) 1421 119 72.83 + 1.63 2.20E-03 regulation of cell proliferation (GO:0042127) 1244 104 63.76 + 1.63 1.79E-02 regulation of localization (GO:0032879) 2121 172 108.71 + 1.58 1.95E-05 cellular response to organic substance (GO:0071310) 1789 145 91.69 + 1.58 5.66E-04 cellular response to chemical stimulus (GO:0070887) 2169 175 111.17 + 1.57 1.97E-05 response to stress (GO:0006950) 2675 214 137.11 + 1.56 2.52E-07 multi-organism process (GO:0051704) 1778 142 91.13 + 1.56 1.82E-03 signaling (GO:0023052) 3676 293 188.41 + 1.56 3.90E-12 signal transduction (GO:0007165) 3430 273 175.80 + 1.55 1.16E-10 cell communication (GO:0007154) 3765 297 192.97 + 1.54 9.19E-12 response to organic substance (GO:0010033) 2277 177 116.71 + 1.52 2.40E-04 regulation of response to stimulus (GO:0048583) 3236 248 165.86 + 1.50 1.96E-07 response to chemical (GO:0042221) 3064 231 157.04 + 1.47 7.21E-06 regulation of biological quality (GO:0065008) 3128 233 160.33 + 1.45 1.69E-05 response to stimulus (GO:0050896) 6023 448 308.71 + 1.45 7.48E-19 regulation of signal transduction (GO:0009966) 2491 182 127.68 + 1.43 7.81E-03 cellular response to stimulus (GO:0051716) 4721 335 241.97 + 1.38 6.26E-08 regulation of cell communication (GO:0010646) 2783 196 142.64 + 1.37 2.76E-02 regulation of signaling (GO:0023051) 2810 197 144.03 + 1.37 3.71E-02 positive regulation of biological process (GO:0048518) 4678 325 239.77 + 1.36 2.43E-06 transport (GO:0006810) 3606 249 184.82 + 1.35 2.82E-03 establishment of localization (GO:0051234) 3707 252 190.00 + 1.33 8.66E-03 positive regulation of cellular process (GO:0048522) 4181 282 214.30 + 1.32 2.13E-03 localization (GO:0051179) 4509 301 231.11 + 1.30 1.34E-03 multicellular organismal process (GO:0032501) 4786 319 245.31 + 1.30 4.57E-04 cellular nitrogen compound metabolic process (GO:0034641) 4383 163 224.65 - .73 8.89E-03 organic cyclic compound metabolic process (GO:1901360) 4192 152 214.86 - .71 3.28E-03 heterocycle metabolic process (GO:0046483) 4012 140 205.63 - .68 5.58E-04 Unclassified (UNCLASSIFIED) 1730 60 88.67 - .68 0.00E00 cellular aromatic compound metabolic process (GO:0006725) 4040 140 207.07 - .68 2.93E-04 cellular macromolecule biosynthetic process (GO:0034645) 2971 101 152.28 - .66 1.80E-02 nucleobase-containing compound metabolic process (GO:0006139) 3880 130 198.87 - .65 6.97E-05 gene expression (GO:0010467) 3159 103 161.91 - .64 8.45E-04 RNA metabolic process (GO:0016070) 2879 91 147.56 - .62 8.35E-04 nucleic acid metabolic process (GO:0090304) 3337 97 171.04 - .57 2.78E-07 mRNA metabolic process (GO:0016071) 618 8 31.68 - .25 1.18E-02 RNA processing (GO:0006396) 763 8 39.11 - .20 2.40E-05 mRNA processing (GO:0006397) 419 3 21.48 - .14 1.37E-02