The conundrum of postpartum thrombotic Microangiopathy: case report and considerations for management
Posted on 2019-03-14 - 05:00
Abstract Background Microangiopathic hemolytic anemias and thrombocytopenias in pregnant or postpartum women constitute an interdisciplinary diagnostic and therapeutic challenge in the evaluation of thrombotic microangiopathies (TMA), where urgent care must be considered. Case presentation We here report the case of a 21-year-old Somali woman, who was delivered by emergency caesarean section at 35âweeks of gestational age with acute dyspnea, placental abruption and gross edema due to severe preeclampsia/HELLP syndrome. After delivery, she developed acute kidney failure and thrombotic microangiopathy as revealed by kidney biopsy. The lack of early response to plasma exchange prompted extensive laboratory workup. Ultimately, the patient completely recovered with negative fluid balance and control of severe hypertension. Conclusions This case report emphasizes the importance to differentiate between primary TMA syndromes and microangiopathic hemolytic anemias due to systemic disorders. Delayed recovery from preeclampsia/HELLP syndrome and malignant hypertension can clinically mimic primary TMA syndromes in the postpartum period.
CITE THIS COLLECTION
DataCite
3 Biotech
3D Printing in Medicine
3D Research
3D-Printed Materials and Systems
4OR
AAPG Bulletin
AAPS Open
AAPS PharmSciTech
Abhandlungen aus dem Mathematischen Seminar der Universität Hamburg
ABI Technik (German)
Academic Medicine
Academic Pediatrics
Academic Psychiatry
Academic Questions
Academy of Management Discoveries
Academy of Management Journal
Academy of Management Learning and Education
Academy of Management Perspectives
Academy of Management Proceedings
Academy of Management Review
Artinger, Katharina; Hackl, Gerald; Schilcher, Gernot; Eisner, Florian; Pollheimer, Marion; Mache, Christoph; et al. (2019). The conundrum of postpartum thrombotic Microangiopathy: case report and considerations for management. figshare. Collection. https://doi.org/10.6084/m9.figshare.c.4435361.v1
or
Select your citation style and then place your mouse over the citation text to select it.
SHARE
Usage metrics
Read the peer-reviewed publication
AUTHORS (9)
KA
Katharina Artinger
GH
Gerald Hackl
GS
Gernot Schilcher
FE
Florian Eisner
MP
Marion Pollheimer
CM
Christoph Mache
EW
Eva-Christine Weiss
KE
Kathrin Eller
PE
Philipp Eller