Influence of deprivation on initial severity and prognosis of patients admitted to the ICU: the prospective, multicentre, observational IVOIRE cohort study
Posted on 2020-02-12 - 04:41
Abstract Background The influence of socioeconomic status on patient outcomes is unclear. We assessed the impact of socioeconomic deprivation on severity of illness at intensive care unit (ICU) admission, and on the risk of death at 3 months after ICU admission. Methods The IVOIRE study was a prospective, observational, multicentre cohort study in the ICU of 8 participating hospitals in France, including patients aged ≥ 18 years admitted to the ICU and receiving at least one life support therapy for organ failure. The primary outcomes were severity at admission (assessed by SAPSII score), and mortality at 3 months. Socioeconomic data were obtained from interviews with patients or family. Deprivation was assessed using the EPICES score. Results Among 1294 patents included between 2013 and 2016, 629 (48.6%) were classed as deprived and differed significantly from non-deprived subjects in terms of sociodemographic characteristics and pre-existing conditions. The mean SAPS II score at admission was 50.1 ± 19.4 in deprived patients and 52.3 ± 17.3 in non-deprived patients, with no significant difference by multivariable analysis (β = − 1.85 [95% CI − 3.86; + 0.16, p = 0.072]). The proportion of death was 31.1% at 3 months, without significant differences between deprived and non-deprived patients, even after adjustment for confounders. Conclusions Deprivation is frequent in patients admitted to the ICU and is not associated with disease severity at admission, or with mortality at 3 months between deprived and non-deprived patients. Trial registration The IVOIRE cohort is registered with ClinicalTrials.gov under the identifier NCT01907581, registration date 17/7/2013
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Quenot, Jean-Pierre; Helms, Julie; Labro, Guylaine; Dargent, Auguste; Meunier-Beillard, Nicolas; Ksiazek, Elea; et al. (2020). Influence of deprivation on initial severity and prognosis of patients admitted to the ICU: the prospective, multicentre, observational IVOIRE cohort study. figshare. Collection. https://doi.org/10.6084/m9.figshare.c.4852707.v1
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AUTHORS (19)
JQ
Jean-Pierre Quenot
JH
Julie Helms
GL
Guylaine Labro
AD
Auguste Dargent
NM
Nicolas Meunier-Beillard
EK
Elea Ksiazek
PB
Pierre-Edouard Bollaert
GL
Guillaume Louis
AL
Audrey Large
PA
Pascal Andreu
CB
Christophe Bein
JR
Jean-Philippe Rigaud
PP
Pierre Perez
RC
Raphaël Clere-Jehl
HM
Hamid Merdji
HD
Hervé Devilliers
CB
Christine Binquet
FM
Ferhat Meziani
IF
Isabelle Fournel