Correspondence on Lovell et al.: identification of chicken genes previously assumed to be evolutionarily lost

Andersson, Leif

Correspondence on Lovell et al.: identification of chicken genes previously assumed to be evolutionarily lost

Posted on 2017-06-14 - 05:00

Abstract Through RNA-Seq analyses, we identified 137 genes that are missing in chicken, including the long-sought-after nephrin and tumor necrosis factor genes. These genes tended to cluster in GC-rich regions that have poor coverage in genome sequence databases. Hence, the occurrence of syntenic groups of vertebrate genes that have not been observed in Aves does not prove the evolutionary loss of such genes. Please see related Research article: http://dx.doi.org/10.1186/s13059-014-0565-1 and Please see response from Lovell et al: https://www.dx.doi.org/10.1186/s13059-017-1234-y

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Bornelรถv, Susanne; Seroussi, Eyal; Yosefi, Sara; Pendavis, Ken; Burgess, Shane; Grabherr, Manfred; et al. (2017). Correspondence on Lovell et al.: identification of chicken genes previously assumed to be evolutionarily lost. figshare. Collection. https://doi.org/10.6084/m9.figshare.c.3803608.v1

https://doi.org/10.6084/m9.figshare.c.3803608.v1

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