Comparative genome sequence analysis underscores mycoparasitism as the ancestral life style of Trichoderma
Posted on 2019-10-24 - 13:09
Abstract Background Mycoparasitism, a lifestyle where one fungus is parasitic on another fungus, has special relevance when the prey is a plant pathogen, providing a strategy for biological control of pests for plant protection. Probably, the most studied biocontrol agents are species of the genus Hypocrea/Trichoderma. Results Here we report an analysis of the genome sequences of the two biocontrol species Trichoderma atroviride (teleomorph Hypocrea atroviridis) and Trichoderma virens (formerly Gliocladium virens, teleomorph Hypocrea virens), and a comparison with Trichoderma reesei (teleomorph Hypocrea jecorina). These three Trichoderma species display a remarkable conservation of gene order (78 to 96%), and a lack of active mobile elements probably due to repeat-induced point mutation. Several gene families are expanded in the two mycoparasitic species relative to T. reesei or other ascomycetes, and are overrepresented in non-syntenic genome regions. A phylogenetic analysis shows that T. reesei and T. virens are derived relative to T. atroviride. The mycoparasitism-specific genes thus arose in a common Trichoderma ancestor but were subsequently lost in T. reesei. Conclusions The data offer a better understanding of mycoparasitism, and thus enforce the development of improved biocontrol strains for efficient and environmentally friendly protection of plants.
CITE THIS COLLECTION
DataCite
3 Biotech
3D Printing in Medicine
3D Research
3D-Printed Materials and Systems
4OR
AAPG Bulletin
AAPS Open
AAPS PharmSciTech
Abhandlungen aus dem Mathematischen Seminar der Universität Hamburg
ABI Technik (German)
Academic Medicine
Academic Pediatrics
Academic Psychiatry
Academic Questions
Academy of Management Discoveries
Academy of Management Journal
Academy of Management Learning and Education
Academy of Management Perspectives
Academy of Management Proceedings
Academy of Management Review
Kubicek, Christian; Herrera-Estrella, Alfredo; Seidl-Seiboth, Verena; Martinez, Diego; Druzhinina, Irina; Thon, Michael; et al. (2011). Comparative genome sequence analysis underscores mycoparasitism as the ancestral life style of Trichoderma. figshare. Collection. https://doi.org/10.6084/m9.figshare.c.4667978.v1
or
Select your citation style and then place your mouse over the citation text to select it.
SHARE
Usage metrics
Read the peer-reviewed publication
AUTHORS (64)
CK
Christian Kubicek
AH
Alfredo Herrera-Estrella
VS
Verena Seidl-Seiboth
DM
Diego Martinez
ID
Irina Druzhinina
MT
Michael Thon
SZ
Susanne Zeilinger
SC
Sergio Casas-Flores
BH
Benjamin Horwitz
PM
Prasun Mukherjee
MM
Mala Mukherjee
LK
László Kredics
LA
Luis Alcaraz
AA
Andrea Aerts
ZA
Zsuzsanna Antal
LA
Lea Atanasova
MC
Mayte Cervantes-Badillo
JC
Jean Challacombe
OC
Olga Chertkov
KM
Kevin McCluskey