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MOESM5 of Combinations of immuno-checkpoint inhibitors predictive biomarkers only marginally improve their individual accuracy

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posted on 2019-04-23, 05:00 authored by Matteo Pallocca, Davide Angeli, Fabio Palombo, Francesca Sperati, Michele Milella, Frauke Goeman, Francesca Nicola, Maurizio Fanciulli, Paola Nisticò, Concetta Quintarelli, Gennaro Ciliberto
Additional file 5: Figure S1. High level workflow for ICI biomarker validation and combination. The N biomarkers were individually tested for each dataset, this test serving as a primary validation of the proposed performance. Mean accuracy was computed for each classifier in all available datasets. Combinatorial analysis was carried out with majority voting and Generalized Linear Models. The E[X] formula stands as an example of the model to create when estimating the a0…aN linear factors.

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Ministero della Salute

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