MOESM1 of Phase I/II intra-patient dose escalation study of vorinostat in children with relapsed solid tumor, lymphoma, or leukemia

van Tilburg, Cornelis; Milde, Till; Witt, Ruth; Ecker, Jonas; Hielscher, Thomas; Seitz, Angelika; Schenk, Jens-Peter; Buhl, Juliane; Riehl, Dennis; Frühwald, Michael; Pekrun, Arnulf; Rossig, Claudia; Wieland, Regina; Flotho, Christian; Kordes, Uwe; Gruhn, Bernd; Simon, Thorsten; Linderkamp, Christin; Sahm, Felix; Taylor, Lenka; Freitag, Angelika; Burhenne, Jürgen; Foerster, Kathrin; Meid, Andreas; Pfister, Stefan; Karapanagiotou-Schenkel, Irini; Witt, Olaf

doi:10.6084/m9.figshare.11352689.v1

13148_2019_775_MOESM1_ESM.pptx (303.53 kB)

MOESM1 of Phase I/II intra-patient dose escalation study of vorinostat in children with relapsed solid tumor, lymphoma, or leukemia

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posted on 2019-12-11, 10:43 authored by Cornelis van Tilburg, Till Milde, Ruth Witt, Jonas Ecker, Thomas Hielscher, Angelika Seitz, Jens-Peter Schenk, Juliane Buhl, Dennis Riehl, Michael Frühwald, Arnulf Pekrun, Claudia Rossig, Regina Wieland, Christian Flotho, Uwe Kordes, Bernd Gruhn, Thorsten Simon, Christin Linderkamp, Felix Sahm, Lenka Taylor, Angelika Freitag, Jürgen Burhenne, Kathrin Foerster, Andreas Meid, Stefan Pfister, Irini Karapanagiotou-Schenkel, Olaf Witt

Additional file 1: Figure S1. a Linear correlation Cmax (ng/mL) – Dose (mg/m2/d). b Concentration of vorinostat in plasma according to dose level.

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Deutsche Kinderkrebsstiftung

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Vorinostat Intra-patient dose escalation Dose-response Cytokine Child HDAC

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MOESM1 of Phase I/II intra-patient dose escalation study of vorinostat in children with relapsed solid tumor, lymphoma, or leukemia

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Deutsche Kinderkrebsstiftung

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