13046_2021_1832_MOESM4_ESM.pptx (40.07 kB)
Additional file 4 of Neuropilin 1 and Neuropilin 2 gene invalidation or pharmacological inhibition reveals their relevance for the treatment of metastatic renal cell carcinoma
presentation
posted on 2021-01-19, 04:39 authored by Aurore Dumond, Etienne Brachet, Jérôme Durivault, Valérie Vial, Anna K. Puszko, Yves Lepelletier, Christopher Montemagno, Marina Pagnuzzi-Boncompagni, Olivier Hermine, Christiane Garbay, Nathalie Lagarde, Matthieu Montes, Luc Demange, Renaud Grépin, Gilles PagèsAdditional file 4: Fig. S3. NRPs KO in 786-O tumor cells inhibited experimental RCC growth in immunodeficient mice. (A) Experimental tumors in nude mice (5 mice per condition) were obtained after injection of 3 × 106 wildtype (Ctrl) or NRPs KO 786-O cells. One NRP1 (#NRP1 2.7) clone and one NRP2 (#NRP2 2.3) clone were injected. Tumor volume is presented. *p < 0.05; **p < 0.01; *** p < 0.001.
