12987_2021_281_MOESM3_ESM.pptx (3.14 MB)
Additional file 3 of A novel model of acquired hydrocephalus for evaluation of neurosurgical treatments
presentation
posted on 2021-11-09, 04:56 authored by James P. McAllister, Michael R. Talcott, Albert M. Isaacs, Sarah H. Zwick, Maria Garcia-Bonilla, Leandro Castaneyra-Ruiz, Alexis L. Hartman, Ryan N. Dilger, Stephen A. Fleming, Rebecca K. Golden, Diego M. Morales, Carolyn A. Harris, David D. LimbrickAdditional file 3: Fig.S3. Representative T2-weighted axial MRI images summarizing brain and ventricular morphology in non-hydrocephalic control (A-E) and hydrocephalic just prior to shunting (A’-E’) pigs. The control pig (case 25) is 41-days old. Pre- shunt images are taken from pig case 13 at 18-days post-kaolin. In the pre-shunt condition, note the enlargement of all cerebral ventricles and the cisterna magna (CM), prominent flow voids (black) within the foramina of Monro (in C’) and third ventricle/cerebral aqueduct (in C’ and D’) indicative of high CSF pulsatility, the patent channel connecting the olfactory ventricle (OV) to the lateral ventricle (LV), and the choroid plexus (CP) floating in the LV. LVt – temporal horn of the lateral ventricle. Scale bar = 10 mm for all panels.
