Additional file 1: of N-Myc promotes therapeutic resistance development of neuroendocrine prostate cancer by differentially regulating miR-421/ATM pathway
posted on 2019-01-18, 05:00authored byYu Yin, Lingfan Xu, Yan Chang, Tao Zeng, Xufeng Chen, Aifeng Wang, Jeff Groth, Wen-Chi Foo, Chaozhao Liang, Hailiang Hu, Jiaoti Huang
Figure S1. (A) Endogenous protein expression of AR, PSA, NSE and CgA in RWPE-1 cells with and without N-Myc overexpression. Immunoblot showed no significant difference between RWPE-1/vector and RWPE-1/N-Myc cells for these protein markers. GAPDH was used as a loading control. (B) Western blotting to show that ATM is not altered in N-Myc-overexpressed RWPE-1 cells, downregulated in N-Myc-overexpressed LNCaP and upregulated in N-Myc-overexpressed C4â2 cells. (PPTX 23818 kb)