12929_2019_565_MOESM8_ESM.pdf (46.13 kB)
MOESM8 of Enrichment of superoxide dismutase 2 in glioblastoma confers to acquisition of temozolomide resistance that is associated with tumor-initiating cell subsets
journal contribution
posted on 2019-10-20, 09:32 authored by Chia-Hung Chien, Jian-Ying Chuang, Shun-Tai Yang, Wen-Bin Yang, Pin-Yuan Chen, Tsung-I Hsu, Chih-Yuan Huang, Wei-Lun Lo, Ka-Yen Yang, Ming-Sheng Liu, Jui-Mei Chu, Pei-Hsuan Chung, Jr-Jiun Liu, Shao-Wen Chou, Shang-Hung Chen, Kwang-Yu ChangAdditional file 8: Figure S8. The correlation between SOD2 and COX4-1. (A) Inverse correlation was noted between COX4–1 and SOD2 in GBM from a web-serve GEPIA ( http://gepia.cancer-pku.cn/ ) using TCGA database (P = 0.03). (B) Levels of COX4–1 and SOD2 in U87MG (left) or A172 (right) were compared to their resistant cells (r#10 or r#6, respectively). The detection was through qPCR for triplicated experiment with standard error shown in the bar graph. (COX4–1 primers: F:5′-GAACGAGTGGAAGACGGTTG, R:5′-GGTTCACCTTCATGTCCAGC).