MOESM1 of Diffusion tensor imaging with direct cytopathological validation: characterisation of decorin treatment in experimental juvenile communicating hydrocephalus

Additional file 1: Figure S1. Decorin prevents ventriculomegaly assessed by T2 weighted MRI images. A bar graph showing a significant increase in ventricular volume in hydrocephalic rats compared to Intact controls. Furthermore, ventriculomegaly was prevented with 2.5 μg/0.5 µl/h infusion of human recombinant decorin treatment; ***p < 0.001. Corresponding representative T2- weighted MRI images displaying the differences in ventricular volume between the experimental groups in the rostral and caudal brain. Arrows highlight the size of the lateral ventricles (LV) or third ventricle (3V). Ventriculomegaly was evident by MRI in the hydrocephalic rats but not in Intact controls or rats that received decorin. Adapted from [12] with permission.