Additional file 1: Figure S1. Venn diagram representing interaction between candida risk factors. Figure S2. Distribution of propensity score of having candidemia, in the study population ("treatment") and the control group ("control") (17), before and after matching. Figure S3. Distribution of propensity score of having candidemia, in the study population ("treatment") and the control group ("control") (17), before and after matching. Figure S4. Standardized mean difference across groups for accounted variables before and after matching. SOFA: Sepsis-related Organ Failure Assessment; RRT: Renal Replacement Therapy; MV: Mechanical ventilation; HSCT: Hematopoietic Stem Cell Transplantation. Figure S5. Kaplan-Meier Survival Curve in patients with Candidemia and in patients without candidemia, before matching (Difference tested using Log-Rank test). Figure S6. Kaplan-Meier Survival Curve in patients with Candidemia and in patients without candidemia, after matching (Difference tested using Log-Rank test). Table S1. Patients characteristics. Table S2. Comparison between ICU acquired candidemia and "primary candidemia" (Patients with candidemia developing before 24h of ICU admission). Table S3. Candidemia patients characteristics and control patients [16] before adjustment. Table S4. Candidemia Patients characteristics and control patients after propensity score matching on gender, organ support, underlying immune defect and stem cell transplantation.