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Additional file 9: of Hypoxia-induced Slug SUMOylation enhances lung cancer metastasis

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posted on 06.01.2019, 05:00 by Pei-Fang Hung, Tse-Ming Hong, Che-Chang Chang, Chung-Lieh Hung, Yuan-Ling Hsu, Yih-Leong Chang, Chen-Tu Wu, Gee-Chen Chang, Nei-Li Chan, Sung-Liang Yu, Pan-Chyr Yang, Szu-Hua Pan
Figure S9. SUMOylation affects the expression of Slug-regulated downstream targets. (a) CL1–5 cells were induced to express the wild-type and mutant Slug, respectively, using a lentiviral system. The mRNA expression of the indicated genes was determined via RT-PCR. Gβ-like was used as the internal control. (b) The protein expression of the Slug downstream target, E-cadherin, in HEK293 (left) and CL1–2 (right) over-expressing Slug wild-type or Slug5M cells. The results were analyzed by immunoblotting with the indicated antibodies. β-actin was used as the internal control. (PDF 174 kb)


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