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Additional file 8 of Receptor deorphanization in an echinoderm reveals kisspeptin evolution and relationship with SALMFamide neuropeptides

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posted on 2022-08-25, 07:11 authored by Nayeli Escudero Castelán, Dean C. Semmens, Luis Alfonso Yañez Guerra, Meet Zandawala, Mario dos Reis, Susan E. Slade, James H. Scrivens, Cleidiane G. Zampronio, Alexandra M. Jones, Olivier Mirabeau, Maurice R. Elphick
Additional file 8. CLuster Analysis of Sequences (CLANS) of A. rubens kisspeptin-type receptors (ArKPR1-11) and other kisspeptin-type receptors from bilaterian taxa. BLOSUM62 cluster map of kisspeptin-type receptors and the closely related galanin/allatostatin-A-type receptors. Nodes are labelled with taxon-specific shapes and colors, as shown in the key. Connections represent BLAST relationships with a P value > 1e-40. Galanin/allatostatin-A-type receptors are enclosed within the dashed line. Names shown in dark blue with an associated symbol containing a blue dot are the receptors for which neuropeptide ligands have been identified experimentally in this study or others. Names shown in black with an associated symbol containing a black dot are A. rubens kisspeptin-type receptors for which neuropeptide ligands have yet to be identified. The accession numbers for the receptors shown in this figure are provided in additional file 3.


Leverhulme Trust Biotechnology and Biological Sciences Research Council CONACyT Mexican Council of Science and Technology CONACyT (Mexican Council of Science and Technology)