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Additional file 7 of m6A modification-mediated BATF2 acts as a tumor suppressor in gastric cancer through inhibition of ERK signaling

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posted on 2020-07-11, 16:07 authored by Jian-Wei Xie, Xiao-Bo Huang, Qi-Yue Chen, Yu-Bin Ma, Ya-Jun Zhao, Li-Chao Liu, Jia-Bin Wang, Jian-Xian Lin, Jun Lu, Long-Long Cao, Mi Lin, Ru-Hong Tu, Chao-Hui Zheng, Chang-Ming Huang, Ping Li
Additional file 7: Figure S2. The effect of BATF2 expression on GC cell proliferation. a MGC-803 and HGC-27 cells with stable BATF2 overexpression or knockdown were created. The changes in BATF2 expression were confirmed using western blotting. b Colony formation and CCK-8 assays with stably transfected MGC-803 cells were performed. Representative images and quantification of the results are presented (**P < 0.01; ***P < 0.001). c Colony formation and CCK-8 assays with stably transfected HGC-27 cells were performed. Representative images and quantification of the results are presented (*P < 0.05; **P < 0.01). d Representative images of Ki-67 IHC staining in xenografted tumors. Scale bars = 200 μm. The Ki-67 IHC scores are shown in the indicated tissues (**P < 0.01).

Funding

National Natural Science Foundation of China Fujian Health Scientific Research Talent Training Program-medical Innovation from Fujian Provincial Health Commission Science and Technology Innovation Joint Fund Project of Fujian Province Fujian Provincial Health Technology Project Youth Research Project of Fujian Province Health and Family Planning Commission

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