posted on 2024-05-14, 04:21authored byLi Hao, Xiaolong Ya, Jiaye Wu, Chuming Tao, Ruochen Ma, Zhiyao Zheng, Siqi Mou, Yiming Ling, Yingxi Yang, Jiguang Wang, Yan Zhang, Qing Lin, Jizong Zhao
Supplementary Material 7: Supplementary Figure 1: Imaging information of 9 patients with intracranial aneurysms (All fusiform aneurysms except AN-05). Supplementary Figure 2:The workflow of Whole-exome sequencing. Supplementary Figure 3: Details of the four mutations located within the PDGFRB gene region. Supplementary Figure 4:Starvation treatment and PDGFBB stimulation. Supplementary Figure 5:Sanger sequencing results of AN-08 and AN-09. Supplementary Figure 6:The infiltration of microglia around the head vasculature in zebrafish. The left side shows the statistical results of microglial cell counts around the blood vessels in zebrafish from each treatment group. The right side shows the infiltration of microglial cells around the head vasculature in zebrafish from each treatment group (red represents microglial cells, green represents blood vessels). Supplementary Figure 7:5-day post-fertilization (dpf) zebrafish locomotor activity: Left panel shows the distance traveled by zebrafish within one hour; Right panel is the heat map, displays the trajectory of zebrafish movement within the same timeframe. Supplementary Table 1:Clinical characteristics and sample details of the nine enrolled patients. Supplementary Table 2: List of primers used in RT-qPCR.
Funding
National Natural Science Foundation of China Beijing Hospital Management Center youth talent training program RGC grants a project of Hetao Shenzhen-Hong Kong Science and Technology Innovation Cooperation Zone