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Additional file 7 of PDGFRβ is an essential therapeutic target for BRCA1-deficient mammary tumors

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posted on 2021-01-23, 00:46 authored by Feng Bai, Shiqin Liu, Xiong Liu, Daniel P. Hollern, Alexandria Scott, Chuying Wang, Lihan Zhang, Cheng Fan, Li Fu, Charles M. Perou, Wei-Guo Zhu, Xin-Hai Pei
Additional file 7. Expression of BRCA1 is inversely related with that of PDGFRβ and PKCα in human breast cancers. (A) Representative immunostaining analysis for serial human breast cancer sections. Antibodies used were indicated. (B) Immunostaining results for individual tumor in (A). +/−, < 2%; +, 2–10%; ++, 10–40%; +++, 40–70%; ++++, > 70%.

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National Natural Science Foundation of China Guangdong Provincial Science and Technology Program High Energy Physics Group, University of Mississippi (US) Natural Science Foundation of Guangdong Province DOD Idea Expansion Award American Cancer Society

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    Breast Cancer Research

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    BRCA1PDGFRβEMTMammary tumorTargeted therapy

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