Springer Nature
Browse
12974_2021_2349_MOESM5_ESM.pdf (1.22 MB)

Additional file 5 of p38-TFEB pathways promote microglia activation through inhibiting CMA-mediated NLRP3 degradation in Parkinson's disease

Download (1.22 MB)
journal contribution
posted on 2021-12-21, 04:42 authored by Jialong Chen, Kanmin Mao, Honglin Yu, Yue Wen, Hua She, He Zhang, Linhua Liu, Mingque Li, Wenjun Li, Fei Zou
Additional file 5: Fig S5. (A, B) Cell apoptosis of SN 4741 cells was detected by flow cytometry dyeing with Annexin V-FITC/PI, followed by the treatment with conditioned medium from BV2. Mean ± SEM, n = 3, *p < 0.05. (C) Balance beam foot slips were quantified after PBS or MCC950 injection demonstrating the protective effect of MCC950. (D) Results of the pole test were quantified after PBS or MCC950 injection demonstrating the protective effect of MCC950. (E, F) Immunofluorescence (IF) staining of synapsin-1 (SYN-1) in the SNpc of mice. Mean ± SEM, n = 6, *p < 0.05.

Funding

National Natural Science Foundation of China national natural science foundation of china discipline construction project of guangdong medical university

History