Additional file 5. Figure S5. Pulmonary score and Lung function test of mice exposed to coal dust for nine months. (A) Pathology score performed by Roderick J. Pathology classification standard of lung injury at three, six, nine-months. (B) Pulmonary fibrosis score performed by Ashcroft Criteria for grading lung fibrosis at three, six, nine -months. (C) Body weight recorded throughout the nine months. (D) The main indexes of lung function are Penh: enhanced pause; Mv: minute volume; Av: accumulated volume; EF50: expiratory flow 50%; PIF: peak inspiratory flow; PEF: peak expiratory flow; F: frequency; Rpef: ratio of time to peak expiratory flow (*p < 0.05, **p < 0.01, ***p < 0.001).
Funding
University Natural Science Research Project of Anhui Province The University Synergy Innovation Program of Anhui Province