13046_2021_2229_MOESM3_ESM.pdf (7.93 MB)
Additional file 3 of ROS/PI3K/Akt and Wnt/β-catenin signalings activate HIF-1α-induced metabolic reprogramming to impart 5-fluorouracil resistance in colorectal cancer
journal contribution
posted on 2022-01-09, 04:11 authored by Shuohui Dong, Shuo Liang, Zhiqiang Cheng, Xiang Zhang, Li Luo, Linchuan Li, Wenjie Zhang, Songhan Li, Qian Xu, Mingwei Zhong, Jiankang Zhu, Guangyong Zhang, Sanyuan HuAdditional file 3: Figure S3. Increased glycolysis and PPP in 5-FU-R CRC cells, related to Fig. 3. a. Unsupervised hierarchical clustering of differential glucose metabolite pools in WT and 5-FU-R CRC cells. b. Comparing basal glycolysis, glycolytic capacity and glycolytic reserve in 5-FU-R CRC cells to WT CRC cells for assessing the glycolytic stress. For all studies n ≥ 3. Data are presented as means ± SEM. Bar chart data were compared by Student’s-t test (* p < 0.05, ** p < 0.01, and *** p < 0.001).
