Additional file 3 of Autocrine insulin-like growth factor 2 signaling as a potential target in the associated development of pulmonary emphysema and cancer in smokers

Additional file 3: Supplementary Fig. 3. Representative IF images and quantitative analysis (n = 7) showing the regulation of IGF2 expression in mice treated with NB for 3 months, those treated with NB for 3 months and withdrawn from NB treatment for 2 months, or those treated with NB for 5 months. Data are the mean ± SD. *p < 0.05; **p < 0.01; ***p < 0.001 (one-way ANOVA with Dunnett’s post-hoc test). Scale bars: 50 μm. 10 μm (insets).