13045_2016_349_MOESM3_ESM.pdf (148.03 kB)

Additional file 3: Figure S2. of A positive feedback loop involving the Wnt/β-catenin/MYC/Sox2 axis defines a highly tumorigenic cell subpopulation in ALK-positive anaplastic large cell lymphoma

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journal contribution
posted on 08.11.2016, 05:00 by Chengsheng Wu, Hai-Feng Zhang, Nidhi Gupta, Abdulraheem Alshareef, Qian Wang, Yung-Hsing Huang, Jamie Lewis, Donna Douglas, Norman Kneteman, Raymond Lai
Inhibition of MYC by MYC-MAD transfection in RR cells significantly decreased the SRR2 luciferase activity. The SRR2 luciferase activity in RR cells derived from SupM2 and Karpas 299 with EV or MYC-MAD transfection at 48 h. The western blots results showed the protein levels of p-MYCS62 and MYC in RR cells from the two cell lines after MYC-MAD transfection at 48 h; cells with EV transfection were included as a control. (PDF 148 kb)

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