12711_2023_784_MOESM2_ESM.docx (234.75 kB)
Additional file 2 of Single-step genome-wide association analyses of claw horn lesions in Holstein cattle using linear and threshold models
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posted on 2023-04-13, 16:15 authored by Bingjie Li, Matthew Barden, Vanessa Kapsona, Enrique Sánchez-Molano, Alkiviadis Anagnostopoulos, Bethany Eloise Griffiths, Cherril Bedford, Xiaoxia Dai, Mike Coffey, Androniki Psifidi, Georgios Oikonomou, Georgios BanosAdditional file 2: Figure S1. Manhattan plots of lesion susceptibility for sole haemorrhage (SH), sole ulcers (SU), and white line disease (WL). The standardized SNP effects were calculated by the estimated SNP effects divided by their empirical standard deviation. The data provided represent the Manhattan plots of the standardized SNP effects for lesion susceptibility of sole haemorrhage (SH), sole ulcers (SU), and white line disease (WL) from the genome-wide association analysis.
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Biotechnology and Biological Sciences Research Council University of Liverpool
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wide association analyseswhite line diseaseimmune system functionfunctional enrichment analysesenhancing foot healthclaw horn lesionscalcium ion activitiesbos taurus chromosomedetailed animal phenotypesbta3 explained 0bta18 explained 0wl provide insightswl also tendedfacilitate genetic improvementthree chl basedfoot lesions includingwl susceptibilitywl ).genetic variancegenetic parametersgenetic correlationsgenetic controlgenetic architecturetwo chlstudy investigatedstudied traitsstudied chlstep genomesole haemorrhagerelatively lowerprimarily causedpositively correlatedpolygenic modeneuronal excitabilitylipid metabolismliability scalelesion susceptibilityinflammation responsesglobal profilegenomic windowdairy cattlecomplex traitschl traitschl susceptibilityanother windowanimal resistance65 mb
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