13024_2017_210_MOESM2_ESM.docx (113.77 kB)
Additional file 2: of Prevention of C5aR1 signaling delays microglial inflammatory polarization, favors clearance pathways and suppresses cognitive loss
journal contribution
posted on 2017-09-18, 05:00 authored by Michael Hernandez, Shan Jiang, Tracy Cole, Shu-Hui Chu, Maria Fonseca, Melody Fang, Lindsay Hohsfield, Maria Torres, Kim Green, Rick Wetsel, Ali Mortazavi, Andrea TennerComparison of IBA1 microglia and Thioflavine S plaque size between Arctic and Arctic/C5aR1KO. (A-D) Representative images of the hippocampus stained for IBA1 and ThioS. (E) Quantification of the number of IBA1+ cells/field of view (FOV) using the spots modules in Bit-plane Imaris 7.5. (F) Quantification of the size of ThioS+ plaques/FOV using the surfaces module in Bit-plane Imaris. Error bars represent SEM, (n = 3–4/group). *p < 0.05. Scale bar in D = 100 μm. (DOCX 113 kb)
