Additional file 2 of MxB impedes the NUP358-mediated HIV-1 pre-integration complex nuclear import and viral replication cooperatively with CPSF6

Additional file 2. MxB inhibits HIV-1WT but not HIV-1N74D viral replication. HeLa-Ctrl and HeLa-MxB cells were synchronously infected with VSV-G pseudotyped HIV-1 luciferase reporter virus bearing either the wild-type (WT) CA or N74D CA mutant. Infectivity was determined 48 h post infection by luciferase assay (a) and p24 protein expression (b). Results were a summary of 3 independent experiments, an unpaired t test was performed (NS, not significant, *p < 0.05, **p < 0.01 and ***p < 0.001).