Additional file 2: Figure S2. of A transcriptional blueprint for a spiral-cleaving embryo

Conservation of early Platynereis gene models in various metazoan species. Our early Platynereis transcriptome comprises of 21,870 gene models with ORFs >100 amino acids that are supported by the Swiss-Prot database, the OrthoMCL analysis, or the EMBL draft 1.90. To further understand the gene/protein evolution of these Platynereis gene models, we constructed orthologous groups among 18 selected species (see OrthoMCL analysis in Methods for details), and determined the number of shared genes between Platynereis and specific groups of species based on two stringent criteria: 1) shared genes must represent the best reciprocal blast hits between each species, and 2) the ORFs must share 50 % identity on the protein level. This figure shows Venn diagrams of the number of genes shared by the three selected species (orange), the number of genes shared between Platynereis and one of the species (yellow and crimson), and the number of genes in Platynereis only (blue). Each of the seven sets shown here contains Platynereis and two different species of similar phylogenetic distance. The 7 sets include: (A) Platynereis dumerilii, and two annelids, the leech Helobdella robusta and the bristle worm Capitella teleta. (B) Platynereis dumerilii, and two spiralian mollusks, the limpet Lottia gigantea and the pacific oyster Crassostrea gigas. (C) Platynereis dumerilii, and two ecdysozoans, the crustacean water flea Daphnia pulex and the insect fruit fly Drosophila melanogaster. (D) Platynereis dumerilii, and two invertebrate deuterostomes, the hemichordate Saccoglossus kowalevskii and the cephalochordate lancelet Branchiostoma floridae. (E) Platynereis dumerilii, and two deuterostome ambulacrarians, the acorn worm Saccoglossus kowalevskii and the echinoderm sea urchin Strongylocentrotus purpuratus. (F) Platynereis dumerilii, and two deuterostome vertebrates, the teleost zebrafish Danio rerio and the mammal human Homo sapiens. (G) Platynereis dumerilii, and two metazoans, the cnidarian sea anemone Nematostella vectensis and the chordate human Homo sapiens. (PDF 102 kb)