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Additional file 1 of Validation of amyloid PET positivity thresholds in centiloids: a multisite PET study approach

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posted on 2021-05-11, 04:00 authored by Sarah K. Royse, Davneet S. Minhas, Brian J. Lopresti, Alice Murphy, Tyler Ward, Robert A. Koeppe, Santiago Bullich, Susan DeSanti, William J. Jagust, Susan M. Landau
Additional file 1: Supplemental Table 1. SUVR and CL values for both FBB and FBP and their respective PiB scans. FBB and FBP scans were processed using the ADNI FS v7.1 pipeline and normalized to the composite reference region: an unweighted average of whole cerebellum, pons, and eroded subcortical white matter. PiB scans were processed using the standard CL pipeline. Supplemental Table 2. VOI volumes for each set of scans used for creating the CL transformation equations. Supplemental Figure 1. Linear regressions of FBB (left) and FBP (right) SUVRs derived from ADNI FS v7.1 pipeline using the composite reference region against PiB SUVRs derived from the standard CL pipeline. A linear conversion from these regressions was used to create “Calculated” PiB SUVRs from FBB and FBP SUVRs. Supplemental Figure 2. A. CL cortex VOI overtop MRI and corresponding PiB PET; B. ADNI FS v7.1 cortex ROI overtop MRI and corresponding FBB PET.

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