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Additional file 1 of Toxicity of Gold Nanoparticles in Mice due to Nanoparticle/Drug Interaction Induces Acute Kidney Damage

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posted on 2020-07-03, 04:33 authored by Katsuhiro Isoda, Anju Tanaka, Chisaki Fuzimori, Miyuki Echigoya, Yuichiro Taira, Ikuko Taira, Yoshimi Shimizu, Yoshihiro Akimoto, Hayato Kawakami, Isao Ishida
Additional file 1: Figure S1. Results of gold nanoparticle diameter measurement. A) GnP10. The average GnP10 diameter indicated by the peak was 15.7 ± 7.0 nm. B) GnP50. The average GnP50 diameter indicated by the peak was 53.3 ± 14.2 nm. C) GnP100. The average GnP100 diameter indicated by the peak was 87.0 ± 27.1 nm. Figure S2. Histologic analysis following a single administration of GnP to mice. At 24-h post-IV administration of only GnP10, Gnp50 or GnP100, the tissues were collected, fixed with 4% paraformaldehyde, sectioned, and stained with hematoxylin and eosin. The liver, heart, kidneys, lungs and spleen were observed.

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