Additional file 1 of The role of testosterone in chronic kidney disease and kidney function in men and women: a bi-directional Mendelian randomization study in the UK Biobank

Additional file 1: Table S1. Associations of genetically predicted total testosterone in men and of genetically predicted bioavailable testosterone in women with CKD and kidney function in the UK Biobank using univariable MR. Table S2. Sensitivity analysis on the associations of genetically predicted bioavailable testosterone in men and of genetically predicted total testosterone in women with CKD and kidney function using different analysis methods in the univariable Mendelian randomization in the UK Biobank. Table S3. Sensitivity analysis excluding genetic variants* related to alcohol in Mendelian randomization in the UK Biobank. Table S4. Sensitivity analysis on the associations of bioavailable testosterone and total testosterone with CKD and kidney function in men and women in the UK Biobank using multivariable MR Egger. Table S5. Associations of genetically predicted total testosterone in men and of genetically predicted bioavailable testosterone in women with hemoglobin and HDL-cholesterol for validation of the genetic instrument in the UK Biobank using univariable and multivariable MR*. Table S6. Genetic predictors for eGFR.