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Additional file 1 of The Revised Self-Monitoring Scale detects early impairment of social cognition in genetic frontotemporal dementia within the GENFI cohort

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posted on 2021-07-13, 03:32 authored by Hannah D. Franklin, Lucy L. Russell, Georgia Peakman, Caroline V. Greaves, Martina Bocchetta, Jennifer Nicholas, Jackie Poos, Rhian S. Convery, David M. Cash, John van Swieten, Lize Jiskoot, Fermin Moreno, Raquel Sanchez-Valle, Barbara Borroni, Robert Laforce, Mario Masellis, Maria Carmela Tartaglia, Caroline Graff, Daniela Galimberti, James B. Rowe, Elizabeth Finger, Matthis Synofzik, Rik Vandenberghe, Alexandre de Mendonça, Fabrizio Tagliavini, Isabel Santana, Simon Ducharme, Chris Butler, Alex Gerhard, Johannes Levin, Adrian Danek, Markus Otto, Sandro Sorbi, Isabelle Le Ber, Florence Pasquier, Jonathan D. Rohrer
Additional file 1: Figure S1. RSMS EX scores in each genetic carrier group, stratified by Global CDR® plus NACC FTLD scores. Significant differences from controls and within each carrier group are starred. Differences between carrier groups are not shown. Figure S2. RSMS SP scores in each genetic carrier group, stratified by Global CDR® plus NACC FTLD scores. Significant differences from controls and within each carrier group are starred. Differences between carrier groups are not shown. Figure S3. Negative correlations between RSMS total and CDR® plus FTLD NACC SOB scores were observed across all mutation carrier groups: C9orf72 (r = -0.67, p < 0.001), GRN (r = -0.59, p < 0.001), MAPT (r = -0.53, p < 0.001). Each dot represents one mutation carrier. Table S1. RSMS total test scores (mean and SD) in healthy controls split by age group. Table S2. Cumulative frequency of RSMS total test scores in healthy controls. Table S3. Adjusted mean differences in RSMS EX scores between the genetic groups stratified by Global CDR® plus NACC FTLD scores with 95% bias-corrected confidence intervals (significant values in bold). Table S4. Adjusted mean differences in RSMS SP scores between the genetic groups stratified by Global CDR® plus NACC FTLD scores with 95% bias-corrected confidence intervals (significant values in bold). Table S5. Correlation of RSMS total test score with cognitive tests. Significant results are in bold. Table S6. Positive neuroanatomical correlates of grey matter volume with the RSMS total score in each genetic group.

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