Additional file 1 of Superstructure-based process synthesis and economic assessment under uncertainty for solid drug product manufacturing

Matsunami, Kensaku; Sternal, Fabian; Yaginuma, Keita; Tanabe, Shuichi; Nakagawa, Hiroshi; Sugiyama, Hirokazu

doi:10.6084/m9.figshare.11840679.v1

42480_2020_28_MOESM1_ESM.docx (782.39 kB)

Additional file 1 of Superstructure-based process synthesis and economic assessment under uncertainty for solid drug product manufacturing

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posted on 2020-02-12, 04:43 authored by Kensaku Matsunami, Fabian Sternal, Keita Yaginuma, Shuichi Tanabe, Hiroshi Nakagawa, Hirokazu Sugiyama

Additional file 1. . This file presents calculation of the number of alternatives in a superstructure, details about the case study, and the contents of “SoliDecision.”

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Daiichi-Sankyo

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Continuous manufacturing Pharmaceutical manufacturing Tablets Formulation Clinical development Process design Alternative generation Decision-making Monte Carlo simulation Sensitivity analysis

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Additional file 1 of Superstructure-based process synthesis and economic assessment under uncertainty for solid drug product manufacturing

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Daiichi-Sankyo

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