Additional file 1 of Prevalence of drug-drug interactions in older people before and after hospital admission: analysis from the OPERAM trial

Additional file 1 Additional file 1 List of potentially clinically significant drug-drug interactions (DDIs) in older people (n = 66). Additional file 2 Classification of drug-drug interactions (DDIs) according to their potential harm. Additional file 3. International Classification of Diseases, 10th revision (ICD-10) codes used to identify comorbid conditions during the index hospitalization. Additional file 4. Prevalence (%) of all drug-drug interactions (DDIs) over time. Additional file 5. The three most common drug-drug interactions (DDIs) in this cohort and medication classes involved. Additional file 6. Prevalence of drug-drug interactions (DDIs) during follow-up (at least one DDI (“whole”) and DDIs belonging to the 3rd most frequent quartile (prevalence ≥1.5%)). A: in the experimental arm, B: in the control arm. Additional file 7. Prevalence of drug-drug interactions (DDIs) during follow-up: at least one DDI for the whole cohort (“whole”) and according to site. Additional file 8. Demographic data and baseline characteristics of older patients included in the cohort and stratified by site. Additional file 9. Demographic data and baseline characteristics of older patients present at 2 months and stratified by DDI decrease status at 2 months compared to baseline. Additional file 10. Demographic data and baseline characteristics of older patients included in our cohort and stratified by DDI increase status at 2 months compared to baseline