Additional file 1 of Point-of-care detection and differentiation of anticoagulant therapy - development of thromboelastometry-guided decision-making support algorithms

Additional file 1: Supplemental Fig. 1. Standard and new thromboelastometric tests are shown under control conditions, intake of anticoagulants and simulated dilutional coagulopathy. Depicted are median + IQR for coagulation time (CT; sec) or clot firmness amplitude 5 min after CT (A5; mm), respectively. A) CTTFTEM, B) A5TFTEM, C) CTECATEM, D) CT-ratio TFTEM/ECATEM, E) CTFIBTEM, and F) A5FIBTEM are differentially altered following DTI (dabigatran), DXaIs, vitamin K antagonists or dilutional coagulopathy. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001; A5: clot firmness amplitude 5 min after CT; CT: coagulation time; DTI: direct thrombin inhibitor; DXaI: direct factor Xa inhibitor; IQR: interquartile range.