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Additional file 1 of Phosphoproteomic profiling of early rheumatoid arthritis synovium reveals active signalling pathways and differentiates inflammatory pathotypes
journal contribution
posted on 2024-06-13, 04:00 authored by Cankut Çubuk, Rachel Lau, Pedro Cutillas, Vinothini Rajeeve, Christopher R. John, Anna E. A. Surace, Rebecca Hands, Liliane Fossati-Jimack, Myles J. Lewis, Costantino PitzalisSupplementary Material 1.
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Barts and The London School of Medicine and Dentistry Medical Research Council National Institute for Health and Care Research Arthritis Research UK Cancer Research UK
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might explain failureincluding mammalian targetidentifying novel biomarkersfree mass spectrometrydas )- 28several phosphosites correlatedintracellular signalling mediatorscdk mediated signallingkinase families ejanus kinase familylymphoproliferative signalling phosphositestotal proteome analysistreatment synovial biopsiesmyeloid ra pathotypesconclusions specific phosphoproteomeactivated protein kinasespecific phosphositesprotein kinaseproteome profilesmyeloid pathotypeprotein levelsphosphosite analysisphosphoproteome analysissynovial tissuewidely usedwhether proteinsstratifying patientsrheumatoid arthritisra therapeuticsra ).previously linkedphosphoproteomic profilingphosphoinositide 3personalised medicineinflammatory stateinflammatory processdirect informationclinical utilityclinical featurescatalytic subunit8 pre
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