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Additional file 1 of Parkinson’s disease–associated VPS35 mutant reduces mitochondrial membrane potential and impairs PINK1/Parkin-mediated mitophagy

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posted on 2021-06-15, 03:22 authored by Kai Yu Ma, Michiel R. Fokkens, Fulvio Reggiori, Muriel Mari, Dineke S. Verbeek
Additional file 1: Fig. S1. Parkin degradation is impaired in VPS35 D620N cells upon CCCP treatment. Fig. S2. CCCP and antimycin A and oligomycin treatments lead to rearrangements of the mitochondrial network.

Funding

Nederlandse Organisatie voor Wetenschappelijk Onderzoek ZonMw TOP ENW-KLEIN Marie Skłodowska-Curie Cofund Marie Skłodowska Curie ETN University of Groningen Jan Kornelis de Cock-Stichting

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    Translational Neurodegeneration

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    Keywords

    VPS35PINK1ParkinMitophagyMitochondrial membrane potentialParkinson’s disease

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    CC BY + CC0

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