Additional file 1 of PGRMC1-dependent lipophagy promotes ferroptosis in paclitaxel-tolerant persister cancer cells

Additional file 1: Figure S1. Paclitaxel-tolerant persister cancer cells (PCC) are vulnerable to xCT inhibitors. Figure S2. Regulation of fatty acid metabolism in PCC modestly increases ferroptosis. Figure S3. FAO or FAS regulation in PCC modestly increases cellular fatty acids. Figure S4. FAO or FAS regulation has minimal effect on lipophagy in PCC. Figure S5. PGRMC1 expression is related to ferroptosis sensitivity. Figure S6. Immunoblotting in HN4 PCC with scrambled or SIRT1 siRNA transfection and then treated with DMSO or 10 μM erastin for 24 h. Table S1. Correlation of mRNA expression levels between PGRMC1 and other genes from the HNC datasets of TCGA.