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Additional file 1 of Lrig1 expression prospectively identifies stem cells in the ventricular-subventricular zone that are neurogenic throughout adult life

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posted on 2020-03-18, 04:49 authored by Hyung-song Nam, Mario R. Capecchi
Additional file 1 Identification of a candidate gene Lrig1 from the Id1high neural stem cells. a Id1-Venus knock-in allele design from [15]. b The Id1-Venus fluorescence responds to changes in exogenous factors such as FGF-2, EGF, and BMP4. c Expression of neurogenic marker gene Ascl1 and oligodendrogliogenic marker gene Olig2 in different cell fractions from these cells. d Diagram of the cells FACS sorted for transcript analysis. e-e”Lrig1 was more highly expressed in the Id1high cell fraction. Mean ± standard deviation.

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Howard Hughes Medical Institute

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