13046_2018_872_MOESM1_ESM.pdf (1.02 MB)
Additional file 1: of Liver cancer cell lines distinctly mimic the metabolic gene expression pattern of the corresponding human tumours
Version 2 2018-11-16, 12:43
Version 1 2018-09-04, 03:47
journal contribution
posted on 2018-11-16, 12:43 authored by Zeribe Nwosu, Nadia Battello, Melanie Rothley, Weronika PioroĹska, Barbara Sitek, Matthias Ebert, Ute Hofmann, Jonathan Sleeman, Stefan WĂślfl, Christoph Meyer, Dominik Megger, Steven DooleyMethods and Figures. Figure S1. Phenotypic and molecular characteristics of HCC cell lines. Figure S2. Overlap of genes deregulated in human HCCÂ datasets, and the top ranked ontology of the highly expressed genes (tumours and poorly differentiated cell lines). Figure S3. Overlap of the gene and protein expression pattern in the cell lines compared with human HCC-tissue derived metabolic genes. Figure S4. Metabolic pathways targeted by the drugs used in this study and the effect of glycolysis inhibition or glutamine withdrawal on the proliferation of HCC cell lines. (DOCX 3020 kb)