Additional file 1: Figure S1. The effect of PF on cell cycle in A549 and PC-9 cells. A549 cells (a) or PC-9 cells (b) were treated with the indicated concentration of PF for 24 h. The left panel shows the flow cytometric analysis of the indicated cells and the right panel shows the statistical analysis of the percentage of cells in G2/M phase of cell cycle. ***P < 0.001. Figure S2. Dkc1 expression in inflammatory non-transformed lung. a The mRNA levels of Dkc1 in lung tissues from smoking mice or sham mice for 6 weeks or 12 weeks (GSE12930). b The mRNA levels of Dkc1 in lung tissues from mice with the indicated treatment (GSE102016). B[a]P: benzo(a)pyrene, LPS: lipopolysaccharides. ns: no significance. Table S1. The Patients’ clinical data and IHC score from LUAD tissue microarray