posted on 2021-04-09, 03:26authored byMarangelie Criado-Marrero, Niat T. Gebru, Danielle M. Blazier, Lauren A. Gould, Jeremy D. Baker, David Beaulieu-Abdelahad, Laura J. Blair
Additional file 1. Fig. S1: Overexpression of Aha1 or FKBP52 increases discrete phospho-tau species in aged wild-type mice. Additional insets from Figure 3 showing the CA1, CA3, and dentate gyrus (DG) from 16-months old wild-type mice expressing AAV9-mCherry, AAV9-Aha1, or AAV9-FKBP52 stained for (a) total tau (Dako), (b) pT231 tau, (c) AT8 (pS202/T205) tau, and (d) pS396 tau, as well as (e) T22 oligomeric tau and (f) Gallyas silver-positive tau. Scale bar represents 10 μm
Funding
National Institute of Neurological Disorders and Stroke National Institute on Aging National Institute of Mental Health U.S. Department of Veterans Affairs Alzheimer's Association