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Additional file 1: of DNA methylation changes at infertility genes in newborn twins conceived by in vitro fertilisation

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posted on 2017-03-24, 05:00 authored by Juan Castillo-Fernandez, Yuk Loke, Sebastian Bass-Stringer, Fei Gao, Yudong Xia, Honglong Wu, Hanlin Lu, Yuan Liu, Jun Wang, Tim Spector, Richard Saffery, Jeffrey Craig, Jordana Bell
Supplementary tables and figures. Table S1 Pregnancy complications and other outcomes. Table S2 PCR assays. Table S3 Re-analysis of FDR 25% WBC IVF-DMRs excluding other fertility treatments from non-IVF group. Table S4 Re-analysis of FDR 25% WBC IVF-DMRs in subset with cell counts. Figure S1 C9orf3 FDR 25% IVF-DMR. Figure S2 H19 CTCF6 IVF-DMR replication. Figure S3 CpG sites targeted for validation. Figure S4 IVF versus non-IVF DNA methylation differences using Sequenom’s EpiTYPER technology. Figure S5 ICSI versus conventional IVF DNA methylation differences using Sequenom’s EpiTYPER technology. Figure S6 H19 CTCF6 IVF-DMR replication using Sequenom’s EpiTYPER technology. (DOCX 104 kb)

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Seventh Framework Programme

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    Genome Medicine

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    Keywords

    In vitro fertilisation (IVF)EpigenomicsDNA methylationMeDIP-seq

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