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Additional file 1 of Cell-free DNA levels associate with COPD exacerbations and mortality
journal contribution
posted on 2024-01-19, 04:41 authored by Sarah A. Ware, Corrine R. Kliment, Luca Giordano, Kevin M. Redding, William L. Rumsey, Stewart Bates, Yingze Zhang, Frank C. Sciurba, S. Mehdi Nouraie, Brett A. KaufmanSupplementary Material 1: Supplementary Methods
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future exacerbation ratescigarette smoke exposureadditional analysis revealed59 – 69obstructive lung diseaserelevant clinical parametersquantitative clinical measurementsndna copy numbersimproving copd severity16 – 201 – 1copd disease severityndna positively associatedincreased mortality riskquestion plasma cfmortality risksevere diseasequestion addressedclinical trajectoriesmortality abstractndna levelsndna abundancecopd longitudinallyprogression assessmentparticipants enrollednatural logmitochondrial genomesmedian agemay aidlow cfinterquartile rangehigh cfhazard ratioglobal initiativefree mitochondrialdetermined associationsconfidence intervalclinical phenotypesbaseline visit128 participants
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